What to know about the Pathogenesis of COPD?

The molecular pathogenesis of COPD is characterized by airway inflammation; however, evidence of the relationship between airway inflammation and epithelial apoptosis is lacking. For decades, necrosis was considered an accidental form of cell death that did not require any specific molecular signaling pathways. Recent studies have demonstrated that a certain degree of necrosis is a well-designed form of cell death; the receptor-interacting protein kinase (RIPK) 3-dependent and caspase-independent programmed necrosis is currently defined as necroptosis. Compared to apoptosis, necroptosis is considered to be a type of programmed cell death involving greater DAMPs release and inflammatory response.

Fast facts about COPD:

COPD is a disease in your lungs that makes it hard to breathe. It's hard to push air out of your lungs. Difficulty pushing air out is called chronic airflow obstruction.

• Smoking cigarettes is the most common cause of COPD
• COPD makes you cough and is short of breath
• Stopping smoking can help keep your airways open
• Your doctor may give you medicines to help avoid or relieve your symptoms
• If you have severe COPD, you may need to take other medicines, use oxygen, or undergo pulmonary (lung) rehabilitation

COPD includes 2 lung disorders—chronic obstructive bronchitis and emphysema. Many people have both disorders.

Chronic obstructive bronchitis: Chronic obstructive bronchitis is a cough that brings up thick fluid (sputum—mucus from your lungs) and lasts for at least 3 months total over 2 or more years in a row, combined with airflow blockage and breathing problems

Emphysema: Emphysema is damage to the air sacs in your lungs

Importance of Pathogenesis of COPD:

The importance of chronic obstructive pulmonary disease (COPD) as a global health problem cannot be overstated. According to the latest World Health Organization (WHO) statistics (2005), approximately 210 million people suffer from COPD worldwide, and 5% of all deaths globally are estimated to be caused by this disease. This corresponds to >3 million deaths annually, of which 90% are thought to occur in low- and middle-income countries. A projection published by the WHO Global Burden of Disease Project indicates that COPD will be the third leading cause of death globally by 2030.[1] Much of this burden will be in the developing populations of Africa, Asia, and the Indian subcontinent. As developing countries can ill afford the added economic burden of COPD, there is an urgent need to understand and address the risk factors for the development of COPD in these countries.

About Respiratory Conference 2023:

The respiratory system is the defining element for all active living beings who breathe air. Recently the covid-19 pandemic has consumed the global human population through respiratory disease, leaving a trail of loss and devastation. Respiratory Conference 2023 invites you to join the “4th International Conference on Respiratory Disease and Care” in Zurich, Switzerland. This Respiratory Conference comes at a very critical time to review what we have learned thus far and what we can propose going forward to protect and prevent situations like SARS-CoV-2 and many others. With this aim, this Respiratory Conference will attract all levels of pulmonologists, researchers, and industry personnel to a common platform for crucial collaborations to secure effective healthcare services for the future. The goal of Longdom Conferences is to bring together scientists at every level from diverse disciplines to understand and discuss throughout the programmed sessions and comfortable gatherings. All these opportunities will support the professional growth of younger scientists that will promote future collaborations and enhance participation and contribution to their exciting research work.

Submit abstract: https://www.longdom.com/respiratoryconference/abstract

Relevant Conferences:

Respiratory Conferences | Respiratory Meetings | Respiratory Workshops | Pulmonology Meetings | Pulmonology Symposiums | Pulmonology Workshops | Pulmonology Conferences | Lung Transplant Conferences |  Lung Transplant workshops | Lung Transplant Meetings | Pulmonary Vascular Diseases Conferences